IMMAGINE
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Epidemiologia
Epidemiology
Componenti
- Ricceri Fulvio (Coordinatore)
- Macciotta Alessandra
- Catalano Alberto
- Dansero Lucia
Contatti
- +39 011 6705440
- fulvio.ricceri@unito.it
- Scrivi a tutti i componenti
Attività
The group of Epidemiology of the Departmental Centre for Biostatistics, Epidemiology and Public Health is composed by a multidisciplinary team involved in the study of the aetiology of non-communicable and communicable diseases.
The two main research interests of the group are:
The study of multimorbidity.
During the last decades, a great increase in life expectancy of developed countries’ populations has been observed leading to an increase of unhealthy conditions due to aging and to a dramatic epidemic of chronic diseases and multimorbidities. Multimorbidity, which can be defined as the co-occurrence of multiple chronic conditions within the same individual, is becoming a great challenge for healthcare systems worldwide.
The group investigates both the different patterns of diseases that occur in the same subjects and the lifestyle and molecular possible causes. A specific focus on SARS-CoV-2 infection is also active.
The study of inequality in health.
The association between health and socioeconomic position is well known and widely
investigated. Many studies in different countries found that health status has a strong socioeconomic gradient. The association between health and social position is detected regardless the proxy indicator of social position and the health outcomes such as chronic diseases, multimorbidity, disability, mortality patterns and overall life expectancy.
The group investigates the possible causal patterns underlying the association between social and health disadvantages. Moreover, specific studies on frail population (e.g.: migrants) are conducted.
To perform this research, the group benefits of data coming from longitudinal studies, mainly: the Turin and Piedmont Longitudinal Study (based on the record-linkage between administrative, health, and census data) and the European Prospective Investigation into Cancer and Nutrition (EPIC) study (a cohort study who recruited about 500,000 subjects in the ‘90s in Europe and is following them up for several chronic diseases).
Il gruppo di Epidemiologia del Centro Dipartimentale di Biostatistica, Epidemiologia e Sanità Pubblica è composto da un team multidisciplinare coinvolto nello studio dell’eziologia delle malattie trasmissibili e non.
I due principali interessi di ricerca sono:
Studio della multimorbidità
Nelle ultime decadi è stato osservato un grande aumento dell’aspettativa di vita nelle popolazioni dei paesi ad alto reddito che ha portato ad un aumento di condizioni di malattia dovute all’invecchiamento e ad un’epidemia di malattie croniche e di multimorbidità. La multimorbidità è definita come la co-occorrenza di patologie croniche multiple nello stesso individuo e sta diventando una grande sfida per i sistemi sanitari mondiali. Il gruppo studia sia i differenti pattern di malattie che si sviluppano nello stesso soggetto, sia le possibili cause molecolari e ambientali. E’ in corso anche un focus sul SARS-CoV-2.
Studio delle disuguaglianze di salute.
L’associazione tra la salute e la posizione socioeconomica è ben nota e ampiamente studiata. Molti studi in differenti nazioni hanno mostrato che la salute ha un forte gradiente socioeconomico. L’associazione tra salute e posizione sociale è inoltre presente qualsiasi indicatore venga usato per la posizione sociale e qualsiasi outcome di salute si studi (malattie croniche, multimorbidità, disabilità, mortalità e speranza di vita). Il gruppo studia i possibili percorsi causali che sottostanno all’associazione tra svantaggio sociale e di salute. In aggiunta, il gruppo studia specifici gruppo di popolazioni fragili (es: le popolazioni migranti).
Per condurre queste ricerche, il gruppo utilizza i dati che provengono da alcuni studi longitudinali, in particolare: gli studi longitudinali torinese e piemontese (costruiti tramite il record-linkage tra i dati amministrativi, sanitari e il censimento) e lo studio prospettico europeo su nutrizione e cancro (EPIC, uno studio di coorte che ha reclutato circa 500.000 soggetti in Europa negli anni 90 e li sta seguendo per identificare alcune patologie croniche).
Progetti
Prodotti della ricerca
Tarekegn A, Ricceri F, Costa G, Ferracin E, Giacobini M. Predictive Modeling for Frailty Conditions in Elderly People: Machine Learning Approaches. JMIR Med Inform. 2020 Jun 4;8(6):e16678
Freisling H, Viallon V, Lennon H, Bagnardi V, Ricci C, Butterworth AS, Sweeting M, Muller D, Romieu I, Bazelle P, Kvaskoff M, Arveux P, Severi G, Bamia C, Kühn T, Kaaks R, Bergmann M, Boeing H, Tjønneland A, Olsen A, Overvad K, Dahm CC, Menéndez V, Agudo A, Sánchez MJ, Amiano P, Santiuste C, Gurrea AB, Tong TYN, Schmidt JA, Tzoulaki I, Tsilidis KK, Ward H, Palli D, Agnoli C, Tumino R, Ricceri F, Panico S, Picavet HSJ, Bakker M, Monninkhof E, Nilsson P, Manjer J, Rolandsson O, Thysell E, Weiderpass E, Jenab M, Riboli E, Vineis P, Danesh J, Wareham NJ, Gunter MJ, Ferrari P. Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study. BMC Med. 2020 Jan 10;18(1):5
Sacerdote C, Ricceri F. Epidemiological dimensions of the association between type 2 diabetes and cancer: a review of observational studies. Diabetes Res Clin Pract. 2018;143:369-377
Ricceri F, Fasanelli F, Giraudo MT, Sieri S, Tumino R, Mattiello A, Vagliano L, Masala G, Quirós JR, Travier N, Sánchez MJ, Larranaga N, Chirlaque MD, Ardanaz E, Tjonneland A, Olsen A, Overvad K, Chang-Claude J, Kaaks R, Boeing H, Clavel-Chapelon F, Kvaskoff M, Dossus L, Trichopoulou A, Benetou V, Adarakis G, Bueno-de-Mesquita HB, Peeters PH, Sund M, Andersson A, Borgquist S, Butt S, Weiderpass E, Skeie G, Khaw KT, Travis RC, Rinaldi S, Romieu I, Gunter M, Kadi M, Riboli E, Vineis P, Sacerdote C. Risk of second primary malignancies in women with breast cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer. Aug 15;137(4):940-948
Bronsino M, Castagneri C, Spinazzola M, Pepe RR, Sacerdote C, Ricceri F. "Journey of hope": a study on sexual gender-based violence reported by asylum-seeking women during their journey to Europe. Epidemiol Prev. 2020 Sep-Dec;44(5-6 Suppl 1):102-106
Ferrante G, Fasanelli F, Gigantesco A, Ferracin E, Contoli B, Costa G, Gargiulo L, Marra M, Masocco M, Minardi V, Violani C, Zengarini N, d'Errico A, Ricceri F. Is the association between precarious employment and mental health mediated by economic difficulties in males? Results from two Italian studies. BMC Public Health. 2019 Jul 3;19(1):869
Stringhini S, Carmeli C, Jokela M, Avendaño M, Muennig P, Guida F, Ricceri F, d’Errico A, Barros H, Bochud M, Chadeau-Hyam M, Clavel-Chapelon F, Costa G, Delpierre C, Fraga S, Goldberg M, Giles G, Krogh V, Kelly Irving M, Layte R, Lasserre AM, Marmot MG, Preisig M, Shipley MJ, Vollenweider P, Zins M, Kawachi I, Steptoe A, Mackenbach JP, Vineis P, Kivimäki M, the LIFEPATH consortium. Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1 × 7 million men and women. 2017 Jan 31. pii: S0140-6736(16)32380-7
Ricceri F, Sacerdote C, Giraudo MT, Fasanelli F, Lenzo G, Galli M, Sieri S, Pala V, Masala G, Bendinelli B, Tumino R, Frasca G, Chiodini P, Mattiello A, Panico R. The association between Socioeconomic Status and Cardiovascular and Cerebrovascular Diseases within the EPICOR study: new evidence for an old inequality problem. PLoS One. Oct 6;11(10):e0164130
Sacerdote C, Ricceri F, Rolandsson O, Baldi I, Chirlaque MD, Feskens E, Bendinelli B, Ardanaz E, Arriola L, Balkau B, Bergmann M, Beulens JWJ, Boeing H, Clavel-Chapelon F, Crowe F, de Lauzon-Guillain B, Forouhi N, Franks P, Gallo V, Gonzalez C, Halkjær J, Illner AK, Kaaks R, Key T, Khaw KT, Navarro C, Nilsson PM, Oksbjerg Dal ton S, Overvad K, Pala V, Palli D, Panico S, Polidoro S, Quirós JR, Romieu I, Sánchez MJ, Slimani N, Sluijs I, Spijkerman A, Teucher B, Tjønneland A, Tumino R, van der A D, Vergnaud AC, Wennberg P, Sharp S, Langenberg C, Riboli E, Vineis P, Wareham N. Lower educational level is a predictor of incident type 2 diabetes in European Countries. The EPIC-InterAct Study. Int J Epidemiology. 2012 Aug; 41(4):1162-73
Caramello V, Macciotta A, Bar F, Mussa A, De Leo AM, De Salve AV, Nota F, Sacerdote C, Ricceri F, Boccuzzi A. The broad spectrum of COVID-like patients initially negative at RT-PCR testing: a cohort study. BMC Public Health. 2022 Jan 7;22(1):45
Caramello V, Boccuzzi A, Basile V, Ferraro A, Macciotta A, Catalano A, Costa G, Vineis P, Sacerdote C, Ricceri F. Are antigenic tests useful for detecting SARS-CoV-2 infections in patients accessing to emergency departments? Results from a North-West Italy Hospital. J Infect. 2021 May 20:S0163-4453(21)00255-3
Fornili M, Petri D, Berrocal C, Fiorentino G, Ricceri F, Macciotta A, Bruno A, Farinella D, Baccini M, Severi G, Baglietto L. Psychological distress in the academic population and its association with socio-demographic and lifestyle characteristics during COVID-19 pandemic lockdown: Results from a large multicenter Italian study. PLoS One. 2021 Mar 10;16(3):e0248370
Caramello V, Maciotta A, De Salve AV, Gobbi V, Ruffino TM, Mazzetti G, Ricagni L, Ling C, Arione R, Boccuzzi A, Costa G, Sacerdote C, Ricceri F. Clinical characteristics and management of COVID-19 patients accessing the emergency department in a hospital in Northern Italy in March and April 2020. Epidemiol Prev. 2020 Sep-Dec;44(5-6 Suppl 2):208-215
Gnavi R, Demaria M, Picariello R, Dalmasso M, Ricceri F, Costa G. Therapy with agents acting on the renin-angiotensin system and risk of SARS-CoV-2 infection. Clin Infect Dis. 2020;71(16):2291-2293